Applied Bioinformatics Group

Department of Biotechnology - University of Verona

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OlfactionDB

 

Odorants are molecules that efficiently carry chemical information, providing one of the main ways for communicating with the environment in all kingdoms of life. In the other hand, mammalian genomes codify for hundreds of olfactory receptors (OR), underlying the crucial role of the sense of smell during evolution, being able to discriminate about 10000 different odors.

OlfactionDB has been developed for managing information about odorants and their receptors. It is a manually curated database that contains information collected from the literature and public databases.

The current version of OlfactionDB contains comprehensive information about

  1. 85 odorants, in terms of molecular formula, number of H-bond donors and acceptors;
  2. 84 odorant receptors, in terms of amino acid sequences, species, and their putative orthologs;
  3. 383 odorant-receptor pairs and their corresponding EC50 values.

A number of online tools have been integrated into the database, to provide the facilities like keyword search, UNIPROT/PubChem accession codes search, sequence similarity search and ligand similarity search.

 

Click here for tutorial.


How to cite: Modena, D.; Trentini, M.; Corsini, M.; Bombaci, A.; Giorgetti, A. OlfactionDB: A Database of Olfactory Receptors and Their Ligands. Advances in Life Sciences 2011; 1(1): 9-13

Authors: Davide Modena, Matteo Trentini, Matteo Corsini, Andrea Bombaci and Alejandro Giorgetti

Dept. of Biotechnology, University of Verona, Italy.