Applied Bioinformatics Group

Department of Biotechnology - University of Verona

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Peer Reviewed

  1. Alice Grison,Silvia Zucchelli,Alice Urzì,Ilaria Zamparo,Dejan Lazarevic,Giovanni Pascarella,Paola Roncaglia,Alejandro Giorgetti,Paula Garcia-Esparcia,Christina Vlachouli,Roberto Simone,Francesca Persichetti,Alistair RR Forrest,Yoshihide Hayashizaki,Paolo Carloni,Isidro Ferrer,Claudia Lodovichi,Charles Plessy,Piero Carninci,Stefano Gustincich, Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules «BMC GENOMICS» , vol. 15 , 2014 , pp. 729-744
  2. S. Piccoli, M. Andreolli, A. Giorgetti, F. Zordan, Silvia Lampis, G. Vallini, Identification of aldolase and ferredoxin reductase within the dbt operon of Burkholderia fungorum DBT1 «JOURNAL OF BASIC MICROBIOLOGY» , vol. 54 , n. 5 , 2014 , pp. 464-469
  3. Alessandra Astegno,Alejandro Giorgetti,Alessandra Allegrini,Barbara Cellini,Paola Dominici, Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs «BIOMED RESEARCH INTERNATIONAL» , vol. 2013 , 2013 , pp. 1-13
  4. Stefano Piccoli,Eda Suku,Marianna Garonzi,Alejandro Giorgetti, Genome-wide Membrane Protein Structure Prediction «CURRENT GENOMICS» , vol. 14 , 2013 , pp. 324-329
  5. Massimo Sandal, Tran Phuoc Duy, Matteo Cona, Hoang Zung, Paolo Carloni, Francesco Musiani, Alejandro Giorgetti, GOMoDo: A GPCRs Online Modeling and Docking Webserver «PLoS ONE» , vol. 8 , n. 9 , 2013 , pp. 1-7
  6. Massimo Sandal,Daniele Paltrinieri,Paolo Carloni,Francesco Musiani,Alejandro Giorgetti, Structure/Function Relationships of Phospholipases C Beta «CURRENT PROTEIN & PEPTIDE SCIENCE» , vol. 14 , 2013 , pp. 650-657
  7. Alessandro Marchiori,Luciana Capece, Alejandro Giorgetti, Paolo Gasparini,Maik Behrens,Paolo Carloni,Wolfgang Meyerhof, Coarse-Grained/Molecular Mechanics of the TAS2R38 Bitter Taste Receptor: Experimentally-Validated Detailed Structural Prediction of Agonist Binding «PLoS ONE» , vol. 8 , n. 5 , 2013 , pp. 1-12
  8. Bisha I, Laio A, Magistrato A, Giorgetti A and Sgrignani J. (2013). A Candidate Ion-Retaining State in the Inward-Facing Conformation of Sodium/Galactose Symporter: Clues from Atomistic Simulations. J. Chem. Theory Comput., 2013, 9 (2), pp 1240–1246
  9. Leguèbe M, Nguyen C, Capece L, Hoang Z, Giorgetti A*, et al. (2012). Hybrid Molecular Mechanics/Coarse-Grained Simulations for Structural Prediction of G-Protein Coupled Receptor/Ligand Complexes. PLoS ONE 7(10): e47332. doi:10.1371/journal.pone.004733
  10. Giorgetti A., P. Ruggerone, S. Pantano, and P. Carloni, Advanced Computational Methods in Molecular Medicine, Journal of Biomedicine and Biotechnology, 2012. 2012: p. 709085.
  11. Zanzoni, S.; Assfalg, M.; Giorgetti, A.; D'Onofrio, M.; Molinari, H.. Structural Requirements for Cooperativity in Ileal Bile Acid Binding Proteins. 2011. J Biol Chem. 2011 Nov 11;286(45):39307-17.
  12. Modena, D.; Trentini, M.; Corsini, M.; Bombaci, A.; Giorgetti, A*. OlfactionDB: A Database of Olfactory Receptors and Their Ligands. Advances in Life Sciences 2011; 1(1): 9-13
  13. Piccoli, S. and Giorgetti A*. Perspectives on Computational Structural Bio-Systems. 2011. J Bioproces Biotechniq 2011,1:104e
  14. Biarnés X.; Marchiori A.; Giorgetti A.*; Lanzara C.; Gasparini P.; Carloni P.; Born S.; Brockhoff A.; Behrens M.; Meyerhof W. (2010). Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor. PLOS ONE, pp. 1- 6 Vol.5
  15. Griguoli M.; Maul A.; Nguyen C.; Giorgetti A.; Carloni P.; Cherubini E. (2010). Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of orienslacunosum molecular interneurons. THE JOURNAL OF NEUROSCIENCE, pp. 10773- 10783 Vol.30
  16. Heller D.M.; Giorgetti A.* (2010). NMR Constraints Analyser: a web-server for the graphical analysis of NMR experimental constraints. NUCLEIC ACIDS RESEARCH, pp. W628- W632 Vol.38
  17. Saga G.; Giorgetti A.; Fufezan C.; Giacometti G.M.; Bassi R.; Morosinotto T. (2010). Mutation analysis of violaxanthin De-epoxidase identifies substrate-binding sites and residues involved in catalysis. THE JOURNAL OF BIOLOGICAL CHEMISTRY, pp. 23763- 23770 Vol.285
  18. Mazzolini M.; Marchesi A.; Giorgetti A.; Torre V. (2010). Gating in CNGA1 channels. PFLUGERS ARCHIV, pp. 547- 555 Vol.459
  19. Maullu C.; Raimondo D.; Caboi F.; Giorgetti A.; Sergi M;. Valentini M.; Tonon G.; Tramontano A. (2009). Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor. THE FEBS JOURNAL, pp. 6741- 6750 Vol.276
  20. Lupieri P.;Nguyen C.H.H. ;Bafghi Z.G.;Giorgetti A.;Carloni P. (2009). Computational molecular biology approaches to ligand-target interactions. HFSP JOURNAL, pp. 228- 239 Vol.3
  21. Raimondo D., Giorgetti A.+, Bernassola F., Melino G., Tramontano A. (2008). Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase Itch and the E2 UbcH7. BIOCHEMICAL PHARMACOLOGY, pp. 1620- 1627 Vol.76
  22. Cozzetto D, Giorgetti A, Raimondo D, Tramontano A. (2008). The Evaluation of Protein Structure Prediction Results.. MOLECULAR BIOTECHNOLOGY, pp. 1- 8 Vol.39
  23. Albiero E., Madeo D., Ruggeri M., Bernardi M., Giorgetti A., Rodeghiero F. (2008). Loss of the JAK2 intramolecular auto-inhibition mechanism is predicted by structural modeling of a novel exon 12 insertion mutation in a case of Idiopathic Erythrocytosis . BRITISH JOURNAL OF HAEMATOLOGY, pp. 986- 990 Vol.142
  24. Tramontano, D. Cozzetto, A. Giorgetti, D. Raimondo.(2007) The assessment of methods for protein structure prediction. Methods in Molecular Biology 413, pp. 43-57
  25. Moutran A, Balan A, Ferreira LC, Giorgetti A, Tramontano A, Ferreira RC. (2007). Structural model and ligand interactions of the Xanthomonas axonopodis pv. citri oligopeptide-binding protein. GENETICS AND MOLECULAR RESEARCH, pp. 1169- 1177 Vol.6
  26. Tress, M., Martelli, P.L., Frankish, A., Reeves, G., Wesselink J.J., Yeats, C., Olason, P.I., Albrecht, M., Hegyi H., Giorgetti, A., Raimondo, D., Lagarde, J., Laskowski, R., Lopez, G., Sadowski, M.I., Watson, J., Fariselli, P., Rossi, I., Nagy, A., Kai, W., Stoerling, Z., Orsini, M., Assenov, Y., Blakenburg, H., Huthmacher, C., Ramirez, F., Schlicker, A., Denoued, F., Jones, P., Kerrien, S., Orchard, S., Birney, E., Brunak, S., Casadio, R., Guigo, R., Harrow, J., Hermjakob, H., Jones, D.T., Lengauer, T., Orengo, C., Patthy, L., Thornton, J., Tramontano, A., Valencia, A. 2007. The implications of alternative splicing in the ENCODE protein complement PROC. NATL ACAD SCI 104: 5495 - 5500
  27. Giorgetti, A., Raimondo, D., Bosi, S. and Tramontano, A. 2007. An automatic procedure for using models of proteins in molecular replacement. PROTEINS. 15;66(3):689-96.
  28. Nair, A.V., Mazzolini,M., Codega, P., Giorgetti, A. and Torre, V. 2006. Locking CNGA1 channels in the open and closed state. BIOPHYSICAL J.  90: 3599-3607
  29. Giorgetti,A., Raimondo, D., Miele, A. and Tramontano, A. 2005. Evaluating the usefulness of protein structure models for molecular replacement. BIOINFORMATICS. 21(suppl_2):ii72-ii76.
  30. Giorgetti A, Carloni P, Mistrik P, Torre V. A Homology Model of the Pore Region of HCN channels. BIOPHYSICAL J. 89(2):932-944
  31. Giorgetti, A., A.V. Nair, P. Codega, V. Torre and P. Carloni. 2005. Structural Basis of Gating of CNG channels. FEBS LETTERS. 579(9):1968-1972.
  32. Giorgetti,A., Carloni,P. 2003. Molecular Modeling of Ion Channels: Structural Predictions. Current Opinion in Chemical Biology. 7: 150-156.

Book chapters

  1. Giorgetti A., S. Piccoli, Knowledge Based Membrane Protein Structure Prediction: From X-Ray Crystallography to Bioinformatics and Back to Molecular Biology, in Current Trends in X-Ray Crystallography, edited by Annamalai Chandrasekaran, InTech Publisher (2011).
  2. Tress M., Casadio R., Giorgetti A., Hallin PF., Juncker AS., Kulberkyte E., Martelli PL., Raimondo D., Reeves GA., Thornton JM., Tramontano A., Wang K., Wesselink JJ., Valencia A., Alternative Splicing in the ENCODE Protein- Complement , Frishman D., Valencia A. Modern Genome Annotation: the Biosapiens Network , Wienn , Springer-Verlag , 2008
  3. Tramontano A., Jones D., Rychlewski L., Casadio R., Martelli PL., Raimondo D., Giorgetti A., Protein structure prediction , Frishman D., Valencia A. Modern Genome Annotation: the Biosapiens Network , Wienn , Springer-Verlag , 2008